I know I have posted a thread about this already, but I doubt anyone will see if I add to that one. I am fairly certain that the problem I am having in 2.49 with the GUI jumping into and out of perspective is caused by a setting in CCC (Catalyst Control Center). Which is the program console that controls my ATI 5570 1gig card. If anyone can give me any clue as to what to change to make this better I'd be eternally greatful. I'm now working with a team on some ages and they all use 2.49 and we're having issues working between 2.6 and 2.49.
I was having a crazy blurry interface in Windows Live Mail and found that it was something in the CCC doing it, so this leads me to believe that is probably what is messing with blender too.