Since you are using Vista, here is something that might help.
1. Right click on the Uru desktop icon and choose properties
2. After the next window opens, click on compatability mode
3. Choose XP SP2
4. Click OK
Lower down in the same window will be a place where you can choose to run as administrator. Put a check in the box and close the window.
Start Uru and see if it helped any. If it did, then good deal!

If it didn't, then I don't know!
